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Terbutaline dose Pediatric IV

-Oral inhalation: If severe attack has not been relieved by the second dosage, higher doses may be required; medical advice should be sought. Use: Prevention and reversal of bronchospasm in patients with asthma and reversible bronchospasm associated with bronchitis and emphysema. Usual Pediatric Dose for Asthma - Maintenance. 6 years or older The dose of terbutaline ranged from 0.05 to 10.0 μg/kg/minute. Patients receiving doses of 0.4 to 2.0 μg/kg/minute required intravenous epinephrine to counteract a drop in diastolic blood pressure (mean, 27 mm Hg; range 10-50). When the terbutaline dose was >2 μg/kg/min, there was no longer need for epinephrine Conclusions: Intravenous terbutaline was well tolerated in asthmatic children for < or =305 continuous hours and at varying doses up to a maximum of 10 microg/kg/min. There was no relationship between the magnitude of CPK-MB concentrations and the terbutaline or epinephrine doses used Conclusions: Terbutaline was found to be safe for use in this patient group in doses ranging between 1 and 5 microg/kg/min. Intravenous terbutaline was found to be a useful adjunct in those who failed to respond to standard initial therapy All patients received nebulized β2 agonists at doses of 2.5 mg/3 mL 3 times back to back, plus 2 mg/kg of IV methylprednisolone as the loading dose, plus 25 to 50 mg/kg of IV magnesium to a maximum dose of 2 g. This treatment was administered to all patients before IV terbutaline

Terbutaline Dosage Guide with Precautions - Drugs

Continuous Intravenous Terbutaline for Pediatric

Conclusions Intravenous terbutaline was well tolerated in asthmatic children for <or=to305 continuous hours and at varying doses up to a maximum of 10 [micro sign]g/kg/min. There was no relationship between the magnitude of CPK-MB concentrations and the terbutaline or epinephrine doses used Terbutaline Refer to dosing table. IV preferred but SQ may be used. Monitor HR & BP closely, and potassium q12 -24 hrs Epinephrine IM 0.01 mg/kg (max 0.3 mg) q 5 min PRN. Ketamine Bolus dose is 0.5 -1 mg/kg. Infusion is 5-20 mcg/kg/min. Titrate to effect. Be ready to intubate if needed IV terbutaline infusions are typically reserved for patients not responding to conventional therapy. For children 5 years and younger, a 2 mcg/kg IV load over 5 minutes, followed by 5 mcg/kg/hour (0.08 mcg/kg/min) continuous IV infusion has been recommended to be used only when inhalational beta-agonist therapy is not possible Terbutaline, 2.5 mg/ml, and placebo for inhalation, and terbutaline, 0.125 mg/ml, and placebo for IV injection, were prepared in identical containers and labeled by code number only

Objective: To determine if the addition of intravenous terbutaline provides any clinical benefit to children with acute severe asthma already on continuous high-dose nebulized albuterol. Methods: We conducted a prospective, randomized, double blind, placebo-controlled trial on pediatric patients with acute severe asthma presenting to a large inner city tertiary children's emergency department Subcutaneous administration of 0.5 mg of terbutaline sulfate to 17 healthy, adult, male subjects resulted in mean (SD) peak plasma terbutaline concentration of 9.6 (3.6) ng/mL, which was observed at a median (range) time of 0.5 (0.08 to 1.0) hours after dosing. The mean (SD) AUC (0 to 48) and total body clearance values were 29.4 (14.2) hr†ng. The usual subcutaneous dose of terbutaline sulfate injection is 0.25 mg injected into the lateral deltoid area. If significant clinical improvement does not occur within 15 to 30 minutes, a second dose of 0.25 mg may be administered Terbutaline can be given subcutaneously, which means injected into the skin, or intravenously (IV), which means given through a vein. The usual dose of terbutaline is 0.25 milligrams (mg) Terbutaline oral tablet is available as a generic drug. It's not available as a brand-name drug. Terbutaline comes as an oral tablet, and as an intravenous (IV) form that's only given by a..

Continuous intravenous terbutaline for pediatric status

To determine whether subcutaneous terbutaline (0.25 mg) would increase the success rate of external cephalic version (ECV) for a breech presentation at term, Fernandez and associates conducted a prospective, randomized, and blind placebo-controlled trial. Of 103 women in the study, 52 received terbutaline and 51 received placebo The usual IV terbutaline doses are 0.1 to 10 μg/kg/min as a continuous infusion, 91 prepared in 0.9% normal saline solution or D 5 W. In our clinical experience, however, most patients are started on a dose of 1 μg/kg/min and the dose is titrated to effect, with doses higher than 4 μg/kg/min rarely necessary

Safety of intravenous terbutaline in acute severe asthma

  1. utes after the first dose, another dose may be given
  2. utes x3 doses until IV established) o If considering IV Terbutaline it m ust be ordered i n concert with STAT PICU consult Recommended starting dose: 10 mcg/kg (max 2 50 mcg) IV load over 15
  3. Although frequently used to treat status asthmaticus in children, intravenous (IV) terbutaline has not been shown to decrease hospital length of stay (LOS)
  4. ute (Titrate prn to 3 mcg/kg/
  5. Dose: 0.1 mg/kg/dose IV x1; Max: 4 mg/dose; Info: give immed. before or after anesthesia induction or shortly postop [>12 yo or >40 kg] Dose: 4 mg IV x1; Info: give immed. before or after anesthesia induction or shortly postop *nausea/vomiting, gastroenteritis-related [8-15 kg] Dose: 2 mg PO x1; Alt: 0.15 mg/kg/dose IV x1; Info: do not cut/chew.

Optimizing the management of children presenting with acute severe asthma is of utmost importance to minimize hospital stays, morbidity, and mortality. Intravenous medications, including theophyllines, are used as second-line treatments for children experiencing a life-threatening exacerbation. For intravenous theophylline (aminophylline), guidelines and formularies recommend a target. Adding a single dose of Intravenous magnesium sulphate to inhaled beta2‐agonists and corticosteroids was more effective, and safer, than using terbutaline or aminophylline when treating a child with acute severe asthma poorly responsive to initial treatment Dose Tocolysis Subcutaneous injection: 250 micrograms stat. For external cephalic version (ECV) give dose Terbutaline is contraindicated in women with cardiac disease. Clinical guidelines and Policies Intravenous Medications - Procedure for Reconstitution and Administration. Drug Dose (IV) Comment Adenosine 0.1 mg/Kg (Max dose: 6 mg) IV Give rapidly No effect in 2 min: 0.2-0.3 mg/Kg (Max dose: 12mg) Albuterol MDI: 4-8 puffs q 20 min with spacer or through ETT Neb: 2.5 mg ( 20 Kg) q 20 min Continuous Neb: 0.5 mg/Kg/hr Asthma, Anaphylaxis, Hyperkalemia Amiodarone 5 mg/Kg IV/IO* Give rapid bolus for V. Fib/pulseless VT Give over 20-60 min for SVT an Suggested Pediatric Drug Dosages 07/05/2005 Zwi Jacob, MD Download 2 page pdf version for printing The dosages and drugs are intended as general guidelines ONLY. The actual drugs and their doses should be administered only following discussion with the attending

terbutaline 10 mcg/kg, Ped Injectable, IV, once, STAT, Loading Dose terbutaline 10 mcg/kg, Ped Injectable, Subcutaneous, once, STAT, Max dose: 0.3 mg, Loading Dose Terbutaline Drip (Pediatric) (IVS)* Diluent volume 30 mL, IV, STAT, Reference Range: 0.1 to 5 mcg/kg/min, Continuous infusion terbutaline (additive) 30 mg, mcg/kg/min EPINEPHrine. Use Terbutaline drip as adjunct , bolus with 10mcg /kg over 10 minutes the run drip .1mcg/kg/min titering q 15-30 min, up to max of 4 mcg/kg/min Consider Ipratroprium neb 0.25-0.5 mg q 4-6° Use Solumedrol 4 mg/kg/day ÷ q6° Consider MgSO4 25-50mg/kg IV q6° Ipratroprium neb 0.25-0.5 mg q 4-6°° Consider temporary NPO statu Each ampoule contains 5mg terbutaline sulfate in 2ml. For the full list of excipients, see section 6.1. 3

[02-17-2011] The U.S. Food and Drug Administration (FDA) is warning the public that injectable terbutaline should not be used in pregnant women for prevention or prolonged treatment (beyond 48-72. Additionally, intravenous terbutaline may be used in children with a severe asthma exacerbation who have not responded to initial therapy. Subcutaneous or intramuscular epinephrine or terbutaline - Typically, subcutaneous For traditional dosing, obtain Trough within 30 min before the next dose and Peak 30 min after 30 min infusion. Goal Peak: 8-10 mcg/mL, synergy 3-4 mcg/mL. Goal Trough: <1 mcg/mL Pediatric Intravenous Antimicrobial Dosing Guideline for Infants and Children >1 month of ag

Early administration of terbutaline in severe pediatric

  1. , duration 5-60
  2. before procedure; not to exceed a total cumulative dose of 0.4 mg/kg or 6 mg. Intramuscular: 0.1-0.2 mg/kg IM 30-45
  3. istration of 0.005-0.01 mg/kg/dose of Terbutaline. If needed, second dose of 0.4 mg can be ad

Intravenous >Using a 1 mL syringe, draw up 0.5 mL (250 micrograms) of terbutaline >Add to a 10 mL syringe and make up to 10 mL with sodium chloride 0.9 % (25 micrograms per mL) >Give intravenous terbutaline slowly in 50 microgram boluses up to 250 micrograms in total (often 100 micrograms will be sufficient Drug Pediatric Dose Codeine Antitussive : PO 1-1.5 mg/kg/day divided q 4-6 hrs Colistin sulfate PO : 100000-300000 unit /kg/day Co-trimoxazole PO ,IV : 6-10 mg TMP/kg/day divided q 12 hrs ( severe : 15-20 mgTMP/kg/day divided q 6-8 hrs ) ( Prophylaxis o Pediatric patients • Drug isn't recommended for use in children younger than age 12. Geriatric patients • These patients are more sensitive to the effects of terbutaline; a lower dose may be required. Patient educatio Commonly Used Medications in PALS Medication recommendations change quickly. It is highly recommended that a pharmacist be included on the resuscitation team to manage all drugs and dosages for pediatric patients. Drug Classification Indications Dose/Administration Possible Side effects Considerations Adenosine Antiarrhythmic SVT 1st dose = 0.1 mg/kg rapid IV push to max of 6 mg [ The maximum dose is 0.5 mg within 4 hours. The recommended dose for the inhaler is 2 puffs every 4 to 6 hours. The dose for preterm labor is 2.5 to 10 mcg/min by intravenous infusion initially, then increase amounts every 10 to 20 minutes. The typical effective dose is 17.5 to 30 mcg/min. Treatment should not exceed 72 hours

A few studies have evaluated the use of high-dose continuous albuterol, with doses as high as 75-150 mg/h, 10 - 12 with no clear evidence of benefit over standard dosing. The limiting factor in continuing to increase the dose of albuterol is typically dose-dependent tachycardia Intravenous β agonists and severe pediatric asthma exacerbation: time for a closer look at terbutaline? Kantor DB(1), Phipatanakul W(2). Author information: (1)Division of Critical Care Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: david.kantor@childrens.harvard.edu

Intravenous Terbutaline in Severe Status Asthmaticus

Terbutaline crosses the placenta. After single dose IV administration of terbutaline to 22 women in late pregnancy who were delivered by elective Cesarean section due to clinical reasons, umbilical blood levels of terbutaline were found to range from 11% to 48% of the maternal blood levels However, the dose is usually not more than 0.5 mg within 4 hours. Children younger than 12 years of age—Use is not recommended. Missed Dose . If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Adverse effects are generally related to the dose of terbutaline and can include tremors, increased heart rate or nervousness. How Terbutaline Is Supplied; Terbutaline is available in 2.5 mg and 5 mg tablets. It is also available in 1 mg/ml injectable form as well as an inhaler form. Dosing Information of Terbutaline Sulfate for Dogs and Cat Before recommending routine use of intravenous terbutaline for acute severe asthma, further study to determine safety and efficacy is necessary. AB - OBJECTIVE: To determine if the addition of intravenous terbutaline provides any clinical benefit to children with acute severe asthma already on continuous high-dose nebulized albuterol

To determine if the addition of intravenous terbutaline provides any clinical benefit to children with acute severe asthma already on continuous high-dose nebulized albuterol For inhalation by dry powder, advise patients and carers not to exceed prescribed dose and to follow manufacturer's directions; if a previously effective dose of inhaled terbutaline fails to provide at least 3 hours relief, a doctor's advice should be obtained as soon as possible.. For inhalation by nebuliser, the dose given by nebuliser is substantially higher than that given by inhaler By infusion: 3 - 5 ml (1.5 - 2.5 mg) in 500 ml 5% dextrose, saline or dextrose/saline given by continuous intravenous infusion at a rate of 10 - 20 drops (0.5 - 1 ml) per minute for 8 to 10 hours.A corresponding reduction in dosage should be made for children. Elderly: Dosage as for adults.. In the short term management of uncomplicated premature labou How to use Terbutaline SULFATE Vial This medication is given by injection under the skin, usually in the shoulder /upper arm area as directed by your doctor. Do not use more than 0.5 milligrams of..

↑ Smith D et al. Intravenous epinephrine in life-threatening asthma. Annals of Emerg Med. May 2003. Volume 41, Issue 5, Pages 706-711. ↑ Kalyanaraman M et al. Serial cardiac troponin concentrations as marker of cardiac toxicity in children with status asthmaticus treated with intravenous terbutaline. Pediatr Emerg Care. 2011 Oct;27(10):933-6 Intravenous aminophylline and salbutamol (or terbutaline) have been compared, head-to-head, in four RCTs involving 202 children. W16-19 Two were conducted in hospital wards, and one in PICU. In one RCT, reported as a conference abstract, the setting was unclear Seven asthmatic children (8-12 years) were given terbutaline sulphate intravenously (5.5 micrograms/kg) and orally (50 micrograms/kg) one week apart. Unchanged terbutaline was measured in plasma and urine. In urine, conjugates were also assayed. The intravenous plasma concentration-time curve declined in a multiexponential manner DOSAGE AND ADMINISTRATION Dosage should be individualized, and patient response should be monitored by the prescribing physician on an ongoing basis. BRICANYL TURBUHALER Adults and Children ≥ 6 Years The generally recommended dose of BRICANYL TURBUHALER (terbutaline sulfate) is one inhalation (0.5 mg) taken as required

Terbutaline - FDA prescribing information, side effects

The primary endpoint was need for escalation in therapy within 24 hours of initial magnesium sulfate dose, defined as need for invasive or non-invasive mechanical ventilation or need for adjunctive therapy, that is, epinephrine, terbutaline, aminophylline, theophylline, ketamine, heliox, or additional doses of magnesium sulfate Terbutaline is available as an injectable, as a metered-dose inhaler, and as tablets in strengths of 2.5 mg and 5 mg. In both dogs and cats, the typical dose of terbutaline as an injectable is 0.005 mg/lb (0.01 mg/kg) every 4 to 6 hours. In tablet form for dogs, the typical dose is 1.25 to 5 mg per dog every 8 hours

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How to use terbutaline. Before you use terbutaline, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about the medicine, and diagrams to remind you how to use and clean your inhaler device; it will also provide you with a full list of the side-effects which you could experience from using it Each dose of terbutaline should control your symptoms for at least 6 hours after you take it. If you find that your symptoms return before it is time for your next dose, that terbutaline does not control your symptoms as well as it did at the beginning of your treatment, or that your symptoms are getting worse, call your doctor Terbutaline is a bronchodilator that is used to treat or prevent bronchospasm (wheezing, chest tightness, trouble breathing) in people with lung conditions such as asthma, bronchitis, or emphysema **Split Load Dose into 3 doses, ½ dose, then ¼ dose x two subsequent doses 8 -12 hours later DIURETICS Chlorothiazide PO: 10-20 mg/kg/dose Q12 IV: 1-4 mg/kg/dose Q12 Furosemide 1-2 mg/kg/dose Q6-Q24 Spironolactone 1 - 3.3 mg/kg/DAY Q12-Q24 Metolazone 0.2-0.4 mg/kg/DAY Q12-Q24 HYPERTENSIVE AGENT

The letter stated that complications of subcutaneous terbutaline administration are similar to that accompanying intravenous administration of terbutaline and other beta-sympathomimetics, including chest pain, tachycardia, dyspnea, pulmonary edema, and death. the risk of total pediatric mortality was significantly higher for infants exposed. TERBUTALINE (BRETHINE) Dosage and Administration Adult: 0.25 mg SQ; may repeat in 1 5-30 min (maximum dose 0 5 mg/4 hr) 400 mcg (two inhalations by MDI) q 4-6 hr; allow 1-2 min between inhalations Pediatric: Not recommended for children under 12 0.01 mg/kg/dose SQ q 15-20 min prn (maximum 0.25 mg dose

Pediatric Intravenous Cannulation: Overview

Brethaire, Brethine (terbutaline) dosing, indications

This study is designed to test the efficacy of intravenous terbutaline for the treatment of status asthmaticus by adding intravenous terbutaline or placebo to standard asthma treatment. The dose of terbutaline or placebo will be titrated according to severity of illness as quantified by a validated clinical asthma score Severe acute asthma (SAA) can lead to respiratory failure and can be fatal. For rational use of intravenous (IV) bronchodilators, evidence regarding the pharmacokinetics and pharmacodynamics is lacking in children. The use of a loading dose IV salbutamol is not mentioned in any international guideline, and its use varies greatly between PICUs worldwide Dose and Usage. The usage, according to medscape.com, is: (Off Label) Preterm Labor. Start at 2.5-5 mcg/min IV; Gradually increase as tolerated at 20-30 minute intervals; Effective dose is between 17.5-30 mcg/min IV, but doses of up to 70-80 mcg/min can be required; Continue use for 12 hours after the uterine contractions cease; do not exceed. Source: Chiang VW, Burns JP, Rifai N, et al. Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment. J Pediatr . 2000 ; 137 : 73 -77. The authors prospectively enrolled 29 children (mean age 9.1 years) treated at Children's Hospital, Boston, MA, who were to receive intravenous terbutaline for severe status asthmaticus that had. Pediatric Asthma Management, Inpatient Admission infusion of terbutaline, aminophylline or ketamine If converting from a q12 or q6 IV dose, start next dose at 9am the next day. If continuing from first dose of 2mg/kg, give dose 24 hours after first dose. Interventions may include supplemental O2 ≤ 4L. If available, patient may.

Terbutaline Sulfate Tablets (terbutaline sulfate) dose

Children's Hospital Association of Texas Safety and Quality Collaborative Asthma Management Pathway (ED and IP) Adjunctive Therapies . Terbutaline Recommendation: Weak recommendation with low-quality evidence to use IV terbutaline in a monitored care setting for the treatment of children with severe asthma exacerbations. Dosage: • Bolu PEDIATRIC DOSING GUIDELINES - ANALGESICS / SEDATIVES DRUG DOSE INTERVAL (hr) Acetaminophen 10 - 15 mg/kg/dose Q4-6 (Max: < 2 years: 60 mg/kg/day; ≥ Albumin2 years: 75 mg/kg/day Max: 4 grams/day) Diazepam Amlodipine** (PO) 0.12 - 0.8 mg/kg/day (Max 10 mg/dose) Q6-8 (IV) 0.04 - 0.3 mg/kg/dose Q6-1 IV: for children, 0.05 mg/kg (up to initial adult dose: 2-5 mg). Repeat/adjust dose as needed for clinical effect. If response to initial dose is inadequate, may double the dose and repeat every 10-20 min as needed to dry pulmonary secretions and achieve anticholinergic effect (atropinization) Antiarrhythmic Agents Drug Dose Route Comments Adenosine 100 mcg/kg Rapid IV push Repeat dose: 200 mcg/kg (Adenocard IV®) Max single dose: 12 mg Amiodarone 5 mg/kg IV Repeat dose: 5 mg/kg (Cordarone®) infused over 30 mins Infusion: 5-10 mcg/kg/min Monitor for hypotension Atropine 0.02 mg/kg IV Min. dose: 0.1 mg Max. dose: 0.5-1.0 m

Comparison of Intravenous and Inhaled Terbutaline in the

phenytoin 20 mg/kg or IV valproate 20 mg/kg with both groups receiving initial therapy with a single dose of IV diazepam 0.2 mg/kg. Successful treatment was defined as cessation of all motor or electroencephalogram seizure activity within 20 minutes following the beginning of the drug infusion. A total of 100 patients were included i For adenosine IV/IO dosage: initiate with a rapid bolus dose of 0.1 mg/kg and increase up to a maximum of 6 mg/kg. This should be followed by a second bolus dose of 0.2 mg/kg and increased up to a maximum of 12 mg/kg. Procainamide IV/IO dosage: over a duration of 30-60 min, administer 15 mg/kg

Comparison of Intravenous Terbutaline Versus Normal Saline

- IV steroids 2 mg/kg up to 125 mg - Consider IV Mg, +/-IM/IV beta agonists, +/- IV Ketamine -No further albuterol Yes-If Continuous Albuterol given, monitor for 1 hour - If CAS still 0, then discharge to home - If CAS >0, then go to next page. CAS 3-4 N terbutaline dose. 0.25 milligrams SQ, May repeat in 15 to 30 minutes. Pediatric Drug Dosage. 15 terms. Ketamine. 15 terms. Dexamethasone. 13 terms. Gastrointestinal Physical and patho phys. IV and heart monitor, medical control. YOU MIGHT ALSO LIKE... 73 terms. AEMT - Medications. 42 terms

Terbutaline Sulfate Injection Us

+ Vancomycin IV* + Clindamycin 13 mg/kg/DOSE IV q8h (max: 900 mg/DOSE) ADD Metronidazole 10 mg/kg/DOSE PO/IV (PO preferred) TID (max: 500 mg/DOSE) if perineum or groin involved Alternative for low/medium-risk allergy4 to cefepime, ceftriaxone, cefotaxime, cefpodoxime, OR high-risk allergy6/contraindication7 to beta-lactams: REPLACE cefepime. For Child 2-14 years 10 micrograms/kg up to 4 times a day (max. per dose 300 micrograms), reserve intravenous beta 2 agonists for those in whom inhaled therapy cannot be used reliably or there is no current effect. For Child 15-17 year The treatment group was treated with oxygen-driven aerosol inhalation of budesonide (suspension) at a dose of 0.5-1.0 mg combined with terbutaline (atomized liquid) (both from Yangze Pharma) at a dose of 2.5 mg terbutaline for children with body weight of <20 kg, and 5.0 mg for those weighing >20 kg

Terbutaline Sulfate (Terbutaline Sulfate): Uses, Dosage

discuss appropriate dosage adjustments in children <1 year of age with impaired renal function. Please use Lexicomp® for dosing in other indications. Refer to the Antimicrobial Stewardship Team website for additional treatment guidelines of infections in pediatric patients. 12 mg/kg/dose IV q8 Pediatric GI bleed dosing has been extrapolated from adult data. May cause transient LFT elevation. Potential for drug interactions: pantoprazole is a CYP 2C19 substrate (and 3A4 to lesser extent); effects on gastric acid excretion may interfere with absorption of drugs dependent on gastric pH Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment. J Pediatr. 2000 Jul. 137(1):73-7. . Kalyanaraman M, Bhalala U, Leoncio M. Serial cardiac troponin concentrations as marker of cardiac toxicity in children with status asthmaticus treated with intravenous terbutaline Neonates (28 days): 0.01-0.03 mg/kg IV of 1: 10,000 solution every 3-5 mins; higher dose not to be given. Neonates (IV access not available): 0.05-0.1 mg/kg endotracheal tube of 1: 10,000 solution; each dose to be followed by at least 5 ml of sodium chloride solution; lower doses are not effective

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Recommended Neonatal Dose, Route, and Interval For airway edema or extubation: 0.25 mg/Kg/dose given IV ~ 4 hours prior to scheduled extubation and then every 8 hours for 3 doses total. Range 0.25-1 mg/kg/dose for 1-3 doses; maximum dose: 1 mg/kg/day. For BPD: 0.075 mg/kg/dose q12 hours for 3 days, 0.05 mg/kg/dose q 12 hours for 3 days , 0.02 EPINEPHRINE - pediatric dose for ALLERGIC REACTION 0.01 mg/kg 1:1,000 SC or IM RAFRACTORY DOSE: 0.01 mg/kg of 1:10,000 IV every 10-15 min ETOMIDATE (Amidate) - adult dose for SEDATION BEFORE INTUBATIO Dose: 0.25 mg SQ every 1-4 hours for 24 hours; Maximum: 5 mg in 24 hours; Intravenous. Start: 10 mcg/minute; Increase rate by 5 mcg per minute every 10 minutes; Maximum: 25 mcg per minute; Once controlled, decrease dose 5 mcg every 30 minutes; Titrate dose down to lowest effective dose; Oral (not effective) Dose: 2.5 to 7.5 mg PO every 1.5 to 4.

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